Potential Drug Delivery Pathways for Treatment of Alzheimer’s Disease

Alzheimer’s Disease (AD) has been one of the most prevalent neurodegenerative disorders that majorly affect patients older than 65 years old. The treatment disease costs over 1% global GDP [1], yet not many new drugs have developed which can effectively treat AD based on its pathological characteristics. major challenge in treating brain such as is Blood-Brain Barrier (BBB) refrains drug molecules from entering brain. Through reviewing multiple papers PubMed Central®(PMC), an archive biomedical and life sciences journal literature at U.S. National Institutes Health’s Library Medicine (NIH/NLM), three promising delivery pathways investigated regarding their capabilities effectivenesses transporting into brain, are inorganic nanoparticles, multifunctional liposomes, transdermal system. In this paper, brief introductions each pathway were offered, specific experiment supported method was presented. advantages, well drawbacks type pathway, also discussed paper.